Research and Publications

From molecular mechanisms to clinical outcomes, CuralysMD™ science is documented in peer-reviewed publications — including mechanistic research, clinical studies, and case reports — across leading dermatology and molecular science journals.

Publications

As a science-first, founder-led dermaceutical platform, our peer-reviewed publications reflect the scientific depth and translational rigor behind CuralysMD™.

Preclinical

Improvements of hydration and epidermal barrier function in human skin by novel compound isosorbide dicaprylate

RK Chaudhuri & K Bojanowski
International J Cosmetic Science, 2017, 39, 518-526
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Isosorbide Di-(linoleate/oleate) stimulates pro-differentiation gene expression to restore the epidermal barrier and improve skin hydration

K Bojanowski, WR Swindell, S Cantor & RK Chaudhuri
J Investigative Dermatology, 2021, 141, 1416-1427
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Isosorbide fatty acid diesters have synergistic anti-inflammatory effects in cytokine-induced tissue culture models of atopic dermatitis

WR Swindell, K Bojanowski & RK Chaudhuri
International J Molecular Science, 2022, 23, 14307
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Isosorbide Diesters: Mechanistic Insights and Therapeutic Applications in Skin and Neuroinflammatory Disorders

RK Chaudhuri & TA Meyer
International J Molecular Science, 2025, 26, 11855.
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Clinical, Case Report & Conceptual

Prospective randomized double-blind vehicle-controlled study of isosorbide diesters based moisturizer on skin health of atopic dermatitis patients

D Nadora, W Burney, RK Chaudhuri, A Galati, CJ Chambers & RK Sivamani
Dermatitis, 2024, 35, S62-S69
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Impact of Isosorbide Diesters from Coconut and Sunflower Fatty Acids on Pediatric Atopic Dermatitis and the Skin Microbiome: A Randomized Double-Blind Vehicle-Controlled Trial

Z Khan, AS. Dulai, A O’Neill, M Min, J Lee, C Dion, N Afzal, RK Chaudhuri, A Lee & RK Sivamani
J Clinical Medicine, 2026, 15, 829
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Rapid Improvement of Pediatric Atopic Dermatitis with a Standardized Isosorbide Diester Moisturizer Used Alongside NB- UVB Phototherapy: A Case Report

S Ndubisi, P Lio
J Integrative Dermatology, 2026, published online
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Advancing Epidermal Barrier Resilience in Atopic Dermatitis with Isosorbide Di-Fatty Acid Esters: From Disruption to Restoration

RK Chaudhuri & RK Sivamani
Biomolecules, 2026, 16, 1246
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Clinical Insights. Real Solutions.

Engage with our team to explore the science behind CuralysMD™ and how our platform redefines eczema care through clinically validated barrier-first dermatology.